Angiotentsinaren entzima bihurtzaile

ACE
	Proteinak kodetzen dituen genea
Identifikadoreak
	Homologene: 37351 Genenames: ACE Ensemble: ENSG00000159640
Taxoia	Homo sapiens
Asoziazio-genetikoa	diabetic nephropathy (en) ; hipertentsio
Kokapena
Kromosoma	human chromosome 17 (en)
Kokapen zitogenetikoa	17q23.3
Hasiera	63477061 bp
Amaiera	63498380 bp
Transkripzioak
RNA ID	XM_006721737, NM_000789, NM_001178057, NM_152830, NM_152831, NM_001382700, NM_001382701, NM_001382702 eta NR_168483
Ensembl	Zerrenda ENST00000584865; ENST00000290863; ENST00000290866; ENST00000413513; ENST00000428043; ENST00000577418; ENST00000578679; ENST00000578839; ENST00000579204; ENST00000579314; ENST00000579462; ENST00000579726; ENST00000580318; ENST00000582005; ENST00000582244; ENST00000582627; ENST00000582678; ENST00000582761; ENST00000583336; ENST00000583645; ENST00000584529;
Sagu arrunt	Ace (en)
Arratoi arrunt	Ace (en)
Danio rerio	ace (en)
Ontologia
Kodetzen du	angiotentsinaren entzima bihurtzaile
Funtzio-molekularrak	Ikusi tripeptidyl-peptidase activity (en) ; zinc ion binding (en) ; exopeptidase activity (en) ; endopeptidase activity (en) ; metal ion binding (en) ; mitogen-activated protein kinase binding (en) ; bradykinin receptor binding (en) ; peptidase activity (en) ; proteina lotura; carboxypeptidase activity (en) ; chloride ion binding (en) ; actin binding (en) ; mitogen-activated protein kinase kinase binding (en) ; hydrolase activity (en) ; metallodipeptidase activity (en) ; metallopeptidase activity (en) ; peptidyl-dipeptidase activity (en) ; metallopeptidase activity (en) ; exopeptidase activity (en) ; dipeptidyl-peptidase activity (en) ; peptidyl-dipeptidase activity (en) ;
Osagai-zelularra	Ikusi zitoplasma; zelula-mintzaren osagai integrala; endosoma; mintza; Lisosoma; extracellular exosome (en) ; external side of plasma membrane (en) ; zelulaz kanpoko eremu; zelula mintz; extracellular space (en) ; extracellular space (en) ; zelula mintz; extracellular exosome (en) ;
Prozesu-biologikoak	Ikusi regulation of renal output by angiotensin (en) ; antigen processing and presentation of peptide antigen via MHC class I (en) ; amyloid-beta metabolic process (en) ; angiotensin maturation (en) ; blood vessel remodeling (en) ; regulation of vasoconstriction (en) ; hematopoietic stem cell differentiation (en) ; regulation of angiotensin metabolic process (en) ; regulation of smooth muscle cell migration (en) ; mononuclear cell proliferation (en) ; regulation of systemic arterial blood pressure by renin-angiotensin (en) ; arachidonic acid secretion (en) ; peptide catabolic process (en) ; blood vessel diameter maintenance (en) ; proteolisi; kidney development (en) ; neutrophil mediated immunity (en) ; positive regulation of systemic arterial blood pressure (en) ; Espermatogenesi; regulation of blood pressure (en) ; posttranscriptional regulation of gene expression (en) ; negative regulation of gene expression (en) ; negative regulation of protein binding (en) ; positive regulation of protein binding (en) ; hormone catabolic process (en) ; heart contraction (en) ; positive regulation of protein tyrosine kinase activity (en) ; cell proliferation in bone marrow (en) ; positive regulation of peptidyl-tyrosine autophosphorylation (en) ; regulation of hematopoietic stem cell proliferation (en) ; negative regulation of gap junction assembly (en) ; positive regulation of peptidyl-cysteine S-nitrosylation (en) ; angiotensin maturation (en) ; regulation of systemic arterial blood pressure by renin-angiotensin (en) ; positive regulation of systemic arterial blood pressure (en) ; positive regulation of blood pressure (en) ;

Angiotentsinaren entzima bihurtzailea (AEB edo ACE) I angiotentsina izeneko substantzia II angiotentsina (giza gorputzeko hodi-uzkurtzailerik indartsuena) bihurtzen duen entzima da. Bradikinina hipotentsorearen inaktibazioa estimulatzen duen II kininasaren berdina da entzima hori, eta, beraz, AEBak funtsezko eginkizuna du presio arterialaren erregulazioan.^[3]. Hainbat gorputz-ehunek sortzen dute, hala nola nerbio-sistema zentralak, giltzurrunak eta birikak.