Nerbio hazkunde-faktore

Identifikadoreak
Taxoia	Homo sapiens
Kokapena
Hasiera
Amaiera
	<div style="position: absolute; left: Adierazpen errorea: Ustekabeko * eragileapx; top: 18px; padding: 0;">[[File:Red rectangle Espresio akatsa: Ez dago operadorerik -(r)entzatx18.png\|Espresio akatsa: Ez dago operadorerik -(r)entzatpx\|link=File:Red rectangle 4x18.png\|alt=kokapena\|]][[File:\|285px\|link=File:\|alt=\|]]
Transkripzioak
Gene-adierazpen eredua
Ontologia
Funtzio-molekularrak	Ikusi peptidase inhibitor activity (en) ; enzyme inhibitor activity (en) ; proteina lotura; metalloendopeptidase inhibitor activity (en) ; nerve growth factor receptor binding (en) ; growth factor activity (en) ; signaling receptor binding (en) ; nerve growth factor receptor binding (en) ;
Osagai-zelularra	Ikusi endosoma; Golgi lumen (en) ; zelulaz kanpoko eremu; cytoplasmic vesicle (en) ; zelulaz kanpoko eremu; extracellular space (en) ; zitosol; synaptic vesicle (en) ; Axoi; Dendrita;
Prozesu-biologikoak	Ikusi negative regulation of neuron apoptotic process (en) ; regulation of neuron differentiation (en) ; neuron projection morphogenesis (en) ; negative regulation of peptidase activity (en) ; neurotrophin TRK receptor signaling pathway (en) ; cell-cell signaling (en) ; negative regulation of apoptotic process (en) ; regulation of cysteine-type endopeptidase activity involved in apoptotic process (en) ; positive regulation of axonogenesis (en) ; positive regulation of gene expression (en) ; positive regulation of apoptotic process (en) ; nerve growth factor processing (en) ; extrinsic apoptotic signaling pathway via death domain receptors (en) ; phosphatidylinositol-mediated signaling (en) ; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process (en) ; microtubule-based movement (en) ; activation of cysteine-type endopeptidase activity involved in apoptotic process (en) ; positive regulation of Ras protein signal transduction (en) ; transmembrane receptor protein tyrosine kinase signaling pathway (en) ; peripheral nervous system development (en) ; Oroimen; negative regulation of cell population proliferation (en) ; regulation of signaling receptor activity (en) ; positive regulation of gene expression (en) ; nerve development (en) ; nerve growth factor signaling pathway (en) ; positive regulation of DNA binding (en) ; positive regulation of neuron differentiation (en) ; positive regulation of collateral sprouting (en) ; neuron projection morphogenesis (en) ; modulation of chemical synaptic transmission (en) ;

Nerbio hazkunde-faktore (NGF) faktore neotrofiko eta neuropeptido bat da, neurona zehatz batzuen hazkuntza, mantenu, hedatze eta biziraupenean parte-hartzen duena. Ziurrenik hazkunde-faktore prototipoa da, eta deskribatu zen lehenetako bat izan zen. Rita Levi-Montalcini eta Stanley Cohenek 1956an isolatu eta Medikuntzako Nobel Saria eskuratu zuten. Garai hartatik hainbat prozesu biologiko aurkitu dira NGFk parte-hartzen duena, horietako bi pankreako beta-zelulen biziraupena eta sistema-immunitarioaren erregulazioa izanik.

Azken urteotako ikerketak aurkitu du NGFren kontzentrazioa odol plasman handiagoa dela harreman erromantiko bat izan dutenen artean 12 hilabete baino gehiagoz, izan ez dutenengan baino^[3].

Erreferentziak aldatu

↑ GRCh38: Ensembl release 89:. Ensembl.
↑ GRCh38: Ensembl release 89:. Ensembl.
↑ EMANUELE, E; POLITI, P; BIANCHI, M; MINORETTI, P; BERTONA, M; GEROLDI, D. «Raised plasma nerve growth factor levels associated with early-stage romantic love» Psychoneuroendocrinology 31 (3): 288–294. doi:10.1016/j.psyneuen.2005.09.002. (Noiz kontsultatua: 2017-10-23).

Kanpo estekak aldatu

Datuak: Q417782
Multimedia: Nerve growth factors

[1] GRCh38: Ensembl release 89:. Ensembl.

[2] GRCh38: Ensembl release 89:. Ensembl.

[3] EMANUELE, E; POLITI, P; BIANCHI, M; MINORETTI, P; BERTONA, M; GEROLDI, D. «Raised plasma nerve growth factor levels associated with early-stage romantic love» Psychoneuroendocrinology 31 (3): 288–294. doi:10.1016/j.psyneuen.2005.09.002. (Noiz kontsultatua: 2017-10-23).

[1]

[2]

[3]

Identifikadoreak
Taxoia	Homo sapiens
Kokapena
Hasiera	^[1]
Amaiera	^[2]
<div style="position: absolute; left: *Adierazpen errorea: Ustekabeko eragileapx; top: 18px; padding: 0;">[[File:Red rectangle Espresio akatsa: Ez dago operadorerik -(r)entzatx18.png\|Espresio akatsa: Ez dago operadorerik -(r)entzat**px\|link=File:Red rectangle 4x18.png\|alt=kokapena\|]] [[File:\|285px\|link=File:\|alt=\|]]
Transkripzioak
Gene-adierazpen eredua

Ontologia
Funtzio-molekularrak	Ikusi peptidase inhibitor activity ^(en) enzyme inhibitor activity ^(en) proteina lotura metalloendopeptidase inhibitor activity ^(en) nerve growth factor receptor binding ^(en) growth factor activity ^(en) signaling receptor binding ^(en) nerve growth factor receptor binding ^(en)
Osagai-zelularra	Ikusi endosoma Golgi lumen ^(en) zelulaz kanpoko eremu cytoplasmic vesicle ^(en) zelulaz kanpoko eremu extracellular space ^(en) zitosol synaptic vesicle ^(en) Axoi Dendrita
Prozesu-biologikoak	Ikusi negative regulation of neuron apoptotic process ^(en) regulation of neuron differentiation ^(en) neuron projection morphogenesis ^(en) negative regulation of peptidase activity ^(en) neurotrophin TRK receptor signaling pathway ^(en) cell-cell signaling ^(en) negative regulation of apoptotic process ^(en) regulation of cysteine-type endopeptidase activity involved in apoptotic process ^(en) positive regulation of axonogenesis ^(en) positive regulation of gene expression ^(en) positive regulation of apoptotic process ^(en) nerve growth factor processing ^(en) extrinsic apoptotic signaling pathway via death domain receptors ^(en) phosphatidylinositol-mediated signaling ^(en) negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ^(en) microtubule-based movement ^(en) activation of cysteine-type endopeptidase activity involved in apoptotic process ^(en) positive regulation of Ras protein signal transduction ^(en) transmembrane receptor protein tyrosine kinase signaling pathway ^(en) peripheral nervous system development ^(en) Oroimen negative regulation of cell population proliferation ^(en) regulation of signaling receptor activity ^(en) positive regulation of gene expression ^(en) nerve development ^(en) nerve growth factor signaling pathway ^(en) positive regulation of DNA binding ^(en) positive regulation of neuron differentiation ^(en) positive regulation of collateral sprouting ^(en) neuron projection morphogenesis ^(en) modulation of chemical synaptic transmission ^(en)