Kaltzitonina

	Peptide hormone (en) eta biogenic peptide (en)
Identifikadoreak
Taxoia	Homo sapiens
Kokapena
Hasiera
Amaiera
	<div style="position: absolute; left: Adierazpen errorea: Ustekabeko * eragileapx; top: 18px; padding: 0;">[[File:Red rectangle Espresio akatsa: Ez dago operadorerik -(r)entzatx18.png\|Espresio akatsa: Ez dago operadorerik -(r)entzatpx\|link=File:Red rectangle 4x18.png\|alt=kokapena\|]][[File:\|285px\|link=File:\|alt=\|]]
Transkripzioak
Ontologia
Funtzio-molekularrak	Ikusi hormone activity (en) ; calcitonin receptor binding (en) ; proteina lotura; identical protein binding (en) ; signaling receptor binding (en) ; calcitonin receptor binding (en) ; calcitonin receptor binding (en) ;
Osagai-zelularra	Ikusi zitoplasma; intrazelular; zelulaz kanpoko eremu; Axoi; terminal bouton (en) ; neuronal cell body (en) ; neuron projection (en) ; zelula nukleo; extracellular space (en) ; extracellular space (en) ; extracellular space (en) ;
Prozesu-biologikoak	Ikusi cellular response to nerve growth factor stimulus (en) ; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway (en) ; negative regulation of smooth muscle contraction (en) ; regulation of heart contraction (en) ; monocyte chemotaxis (en) ; negative regulation of blood pressure (en) ; positive regulation of cytosolic calcium ion concentration (en) ; cellular response to tumor necrosis factor (en) ; Giza zahartze; basodilatazio; zelulako kaltzio ioi homeostasia; response to heat (en) ; negative regulation of nervous system process (en) ; positive regulation of ossification (en) ; activation of adenylate cyclase activity (en) ; regulation of heart rate (en) ; detection of temperature stimulus involved in sensory perception of pain (en) ; negative regulation of ossification (en) ; response to pain (en) ; artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure (en) ; feeding behavior (en) ; inflammatory response (en) ; neuropeptide signaling pathway (en) ; negative regulation of transcription, DNA-templated (en) ; activation of protein kinase activity (en) ; embryo implantation (en) ; negative regulation of bone resorption (en) ; regulation of signaling receptor activity (en) ; G proteina errezeptore akoplatuaren komunikazio bidea; adenylate cyclase-activating G protein-coupled receptor signaling pathway (en) ; adenylate cyclase-activating G protein-coupled receptor signaling pathway (en) ; regulation of cytosolic calcium ion concentration (en) ; adenylate cyclase-activating G protein-coupled receptor signaling pathway (en) ;

Kaltzitonina tiroide guruinaren zelula parafolikularrek sintetizatzen duten hormona da. Hormona honek odoleko kaltzio eta fosfato kontzentrazioak murrizten ditu.

Odolean kaltzio kontzentrazioaren igoera bat ematen denean tiroidea aktibatu egiten da eta kaltzitonina jariatzen hasten da. Kaltzitoninak efektu fisiologiko desberdinak izango ditu:

Giltzurrunean kaltzio eta fosfatoaren birxurgapena gutxitzen du.
Hezurretan osteoklastoak inhibitu eta osteoblastoak aktibatzen ditu. Horren eraginez, hezurraren birxurgapena edo erreabsortzioa moteltzen da eta kaltzioa odoletik hezurretara pasatzen da.

Izokinaren kaltzitonina hainbat gaixotasunen tratamenduan erabili izan da:

Erreferentziak aldatu

↑ GRCh38: Ensembl release 89:. Ensembl.
↑ GRCh38: Ensembl release 89:. Ensembl.

Kanpo estekak aldatu

Datuak: Q315860
Multimedia: Calcitonin / Q315860

[1] GRCh38: Ensembl release 89:. Ensembl.

[2] GRCh38: Ensembl release 89:. Ensembl.

[1]

[2]

Identifikadoreak
Peptide hormone ^(en) eta biogenic peptide ^(en)
Taxoia	Homo sapiens
Kokapena
Hasiera	^[1]
Amaiera	^[2]
<div style="position: absolute; left: *Adierazpen errorea: Ustekabeko eragileapx; top: 18px; padding: 0;">[[File:Red rectangle Espresio akatsa: Ez dago operadorerik -(r)entzatx18.png\|Espresio akatsa: Ez dago operadorerik -(r)entzat**px\|link=File:Red rectangle 4x18.png\|alt=kokapena\|]] [[File:\|285px\|link=File:\|alt=\|]]
Transkripzioak
Ontologia
Funtzio-molekularrak	Ikusi hormone activity ^(en) calcitonin receptor binding ^(en) proteina lotura identical protein binding ^(en) signaling receptor binding ^(en) calcitonin receptor binding ^(en) calcitonin receptor binding ^(en)
Osagai-zelularra	Ikusi zitoplasma intrazelular zelulaz kanpoko eremu Axoi terminal bouton ^(en) neuronal cell body ^(en) neuron projection ^(en) zelula nukleo extracellular space ^(en) extracellular space ^(en) extracellular space ^(en)
Prozesu-biologikoak	Ikusi cellular response to nerve growth factor stimulus ^(en) positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway ^(en) negative regulation of smooth muscle contraction ^(en) regulation of heart contraction ^(en) monocyte chemotaxis ^(en) negative regulation of blood pressure ^(en) positive regulation of cytosolic calcium ion concentration ^(en) cellular response to tumor necrosis factor ^(en) Giza zahartze basodilatazio zelulako kaltzio ioi homeostasia response to heat ^(en) negative regulation of nervous system process ^(en) positive regulation of ossification ^(en) activation of adenylate cyclase activity ^(en) regulation of heart rate ^(en) detection of temperature stimulus involved in sensory perception of pain ^(en) negative regulation of ossification ^(en) response to pain ^(en) artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure ^(en) feeding behavior ^(en) inflammatory response ^(en) neuropeptide signaling pathway ^(en) negative regulation of transcription, DNA-templated ^(en) activation of protein kinase activity ^(en) embryo implantation ^(en) negative regulation of bone resorption ^(en) regulation of signaling receptor activity ^(en) G proteina errezeptore akoplatuaren komunikazio bidea adenylate cyclase-activating G protein-coupled receptor signaling pathway ^(en) adenylate cyclase-activating G protein-coupled receptor signaling pathway ^(en) regulation of cytosolic calcium ion concentration ^(en) adenylate cyclase-activating G protein-coupled receptor signaling pathway ^(en)